Investigation of electrospun poly (<i>ε</i>-caprolactone) fiber mats loaded with <i>Calophyllum inophyllum</i> essential oil for wound dressing applications: Morphology, drug release and in vitro evaluation

In this study, Calophyllum inophyllum (CIO) loaded Poly (ε-caprolactone) (PCL) electrospun fibre mats were produced for potential wound healing applications. Physiochemical evaluation and in vitro characterisation of evaluated. Average diameters the determined as 0.9 ± 0.3 μm, 1.2 0.2 1.3 1.5 0.1 μm PCL, PCL/CIO−2.5, PCL/CIO−5 PCL/CIO−7.5, respectively. The contact angle values decreased up to 30 5 (°) compared oil-free PCL mat, indicating improved surface wettability. incorporation CIO into led a two-fold increase antibacterial activity, composed PCL. cytotoxicity indicated that all had increased cell viability control. findings suggest CIO-loaded have use tissue engineering